Rapid mask prototyping for microfluidics     

B. G. C. Maisonneuve  T. Honegger  J. Cordeiro  O. Lecarme  T. Thiry  D. Fuard  K. Berton  E. Picard  M. Zelsmann  D. Peyrade 《Biomicrofluidics》2016,10(2)

With the rise of microfluidics for the past decade, there has come an ever more pressing need for a low-cost and rapid prototyping technology, especially for research and education purposes. In this article, we report a rapid prototyping process of chromed masks for various microfluidic applications. The process takes place out of a clean room, uses a commercially available video-projector, and can be completed in less than half an hour. We quantify the ranges of fields of view and of resolutions accessible through this video-projection system and report the fabrication of critical microfluidic components (junctions, straight channels, and curved channels). To exemplify the process, three common devices are produced using this method: a droplet generation device, a gradient generation device, and a neuro-engineering oriented device. The neuro-engineering oriented device is a compartmentalized microfluidic chip, and therefore, required the production and the precise alignment of two different masks.  相似文献   

Content valuation strategies for digital subscription platforms     

Kübler  Raoul  Seifert  Rouven  Kandziora  Michael 《Journal of Cultural Economics》2021,45(2):295-326

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Why all scientists write in English     

Gross  Alan G. 《Metascience》2016,25(1):125-129

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A Note from the Editor: Introducing Our Spanish Language Articles     

Michael G Moore 《The American journal of distance education》2020,34(1):1-2

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Warum scheiterte 1920 August Biers Antrag auf einen „Doktor der Leibesübungen“?     

Univ.-Prof. Dr. Jürgen Court 《Sportwissenschaft》2011,41(2):91-99

This article deals with the first years of foundation of the private Deutsche Hochschule für Leibesübungen (DHfL). It focuses on the question of why August Bier’s application for a Doktor der Leibesübungen in 1920 was refused. In the same year the DHfL also made an application for the education in state-run schools which was already task of the state-run Preußische Landesturnanstalt at Spandau. As the DHfL combined this application with its insistence on its autonomous status an application for a Doktor der Leibesübungen had implied financial, conceptual and institutional obligations for Prussia and at the same time a renuncitation of its sovereign rights. This thesis was proved by a comparison between the doctorate in physical education and the doctorate for businessmen at Cologne University.  相似文献   

The relative age effect on physical fitness in preschool children     

Rocío Cupeiro  Miguel A. Rojo-Tirado  Cristina Cadenas-Sanchez  Enrique G. Artero  Ana B. Peinado  Idoia Labayen 《Journal of sports sciences》2020,38(13):1506-1515

ABSTRACT

The aim of the present study was to investigate the existence of a relative age effect (RAE) on physical fitness of preschoolers. Anthropometry and physical fitness were assessed in 3147 children (3–5 years old) using the PREFIT battery. Based on the birth year, participants were divided into 3year groups (3-, 4- and 5-years). Within each year group, 4quarter groups were created: quarter 1, preschoolers born from January to March; quarter 2, from April to June; quarter 3, from July to September; quarter 4, from October to December. The MANCOVA analysis revealed a main effect of year group (Wilks’ λ = 0.383; F_10,5996 = 369.64; p < 0.001, η_p ² = 0.381) and of quarter (Wilks’ λ = 0.874; F_15,8276.6 = 27.67; p < 0.001; η_p ² = 0.044) over the whole battery of tests. To the best of our knowledge, this is the first study to report the existence of RAE at the preschool stage. In general, performance improved as the relative age increased (i.e., those born in quarter 1 performed better than those in the other quarters). Individualization strategies should be addressed within the same academic year not only in elementary or secondary years but also in preschoolers.  相似文献   

Neuroanatomy Learning: Augmented Reality vs. Cross-Sections     

Dylan J.H.A. Henssen  Loes van den Heuvel  Guido De Jong  Marc A.T.M. Vorstenbosch  Anne-Marie van Cappellen van Walsum  Marianne M. Van den Hurk  Jan G.M. Kooloos  Ronald H.M.A. Bartels 《Anatomical sciences education》2020,13(3):353-365

Neuroanatomy education is a challenging field which could benefit from modern innovations, such as augmented reality (AR) applications. This study investigates the differences on test scores, cognitive load, and motivation after neuroanatomy learning using AR applications or using cross-sections of the brain. Prior to two practical assignments, a pretest (extended matching questions, double-choice questions and a test on cross-sectional anatomy) and a mental rotation test (MRT) were completed. Sex and MRT scores were used to stratify students over the two groups. The two practical assignments were designed to study (1) general brain anatomy and (2) subcortical structures. Subsequently, participants completed a posttest similar to the pretest and a motivational questionnaire. Finally, a focus group interview was conducted to appraise participants’ perceptions. Medical and biomedical students (n = 31); 19 males (61.3%) and 12 females (38.7%), mean age 19.2 ± 1.7 years participated in this experiment. Students who worked with cross-sections (n = 16) showed significantly more improvement on test scores than students who worked with GreyMapp-AR (P = 0.035) (n = 15). Further analysis showed that this difference was primarily caused by significant improvement on the cross-sectional questions. Students in the cross-section group, moreover, experienced a significantly higher germane (P = 0.009) and extraneous cognitive load (P = 0.016) than students in the GreyMapp-AR group. No significant differences were found in motivational scores. To conclude, this study suggests that AR applications can play a role in future anatomy education as an add-on educational tool, especially in learning three-dimensional relations of anatomical structures.  相似文献   

Eugenics: Then and now     

Staffan Müller-Wille 《Metascience》2011,20(2):347-349

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Evidence for data missing at random in youth physical activity monitoring research     

P. F. Saint-Maurice  Y. Kim  G. J. Welk 《Journal of sports sciences》2017,35(5):484-490

This study examined whether or not activity monitor data collected as part of a typical 7-day physical activity (PA) measurement protocol can be expected to be missing at random. A total of 315 participants (9–18 years) each wore a SenseWear Armband monitor for 7 consecutive days. Participants were classified as “compliant” (86 boys and 124 girls) if they had recorded accelerometer data during 70% or more of the predefined awake time (7 AM–10 PM) on four different days; and “non-compliant” (44 boys and 51 girls) when not meeting these criteria. Linear mixed models were used to examine differences in energy expenditure (EE) levels by compliance across 10 different time periods. The results indicated that non-compliant girls were older (13.4 ± 2.9 vs. 12.2 ± 2.5) and taller (156.8 ± 10.3 vs. 152.8 ± 11.3) than their same gender compliant peers (P < .05). Comparisons of EE rates at segmented portions of the day revealed no differences between compliant and non-compliant groups (P ≥ .05). Differences in EE ranged from ?0.32 kcal · kg^?1 · h^?1 (before school time) to 0.62 kcal · kg^?1 · h^?1 (physical education class) in boys and ?0.39 kcal · kg^?1 · h^?1 (transportation from school) to 0.37 kcal · kg^?1 · hour^?1 (recess) in girls. The results showed that compliant and non-compliant individuals differed in a few demographic characteristics but exhibited similar activity patterns. This suggests that data were considered to be missing at random, but additional work is needed to confirm this observation in a representative sample of children using other types of activity monitors and protocols.  相似文献   

Tribute to Dr Jacques Rogge: muscle activity and fatigue during hiking in Olympic dinghy sailing     

Jan G. Bourgois  Jasmien Dumortier  Margot Callewaert  Bert Celie  Carlo Capelli  Gisela Sjøgaard 《European Journal of Sport Science》2017,17(5):611-620

‘A tribute to Dr J. Rogge’ aims to systematically review muscle activity and muscle fatigue during sustained submaximal quasi-isometric knee extension exercise (hiking) related to Olympic dinghy sailing as a tribute to Dr Rogge’s merits in the world of sports. Dr Jacques Rogge is not only the former President of the International Olympic Committee, he was also an orthopaedic surgeon and a keen sailor, competing at three Olympic Games. In 1972, in fulfilment of the requirements for the degree of Master in Sports Medicine, he was the first who studied a sailors’ muscle activity by means of invasive needle electromyography (EMG) during a specific sailing technique (hiking) on a self-constructed sailing ergometer. Hiking is a bilateral and multi-joint submaximal quasi-isometric movement which dinghy sailors use to optimize boat speed and to prevent the boat from capsizing. Large stresses are generated in the anterior muscles that cross the knee and hip joint, mainly employing the quadriceps at an intensity of 30–40% maximal voluntary contraction (MVC), sometimes exceeding 100% MVC. Better sailing level is partially determined by a lower rate of neuromuscular fatigue during hiking and for ≈60% predicted by a higher maximal isometric quadriceps strength. Although useful in exercise testing, prediction of hiking endurance capacity based on the changes in surface EMG in thigh and trunk muscles during a hiking maintenance task is not reliable. This could probably be explained by the varying exercise intensity and joint angles, and the great number of muscles and joints involved in hiking.

Highlights

• Dr Jacques Rogge, former president of the International Olympic Committee and Olympic Finn sailor, was the first to study muscle activity during sailing using invasive needle EMG to obtain his Master degree in Sports Medicine at the Ghent University.

• Hiking is a critical bilateral and multi-joint movement during dinghy racing, accounting for >60% of the total upwind leg time. Hiking generates large stresses in the anterior muscles that cross the knee and hip joint.

• Hiking is considered as a quasi-isometric bilateral knee extension exercise. Muscle activity measurements during sailing, recorded by means of EMG, show a mean contraction intensity of 30-40% maximal voluntary contraction with peaks exceeding 100%.

• Hiking performance is strongly related to the development of neuromuscular fatigue in the quadriceps muscle. Since maximal strength is an important determinant of neuromuscular fatigue during hiking, combined strength and endurance training should be incorporated in the training program of dinghy sailors.

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